文章摘要
付东,王珏,李鹏,黄波,谢洋,阚侃.长链N-烷基-3-甲基吡啶溴盐表面活性剂合成及其性能[J].精细化工,2019,36(4):0
长链N-烷基-3-甲基吡啶溴盐表面活性剂合成及其性能
Synthesis and Properties of Surfactants: Long-Chain n-Alkyl-3-Methylpyridinium Bromide
投稿时间:2018-07-09  修订日期:2018-11-05
DOI:
中文关键词: N-烷基-3-甲基吡啶溴盐  电导率法  胶束化行为  热力学  抑菌活性
英文关键词: n-Alkyl-3-methylpyridinium bromide  micellization  conductometry  thermodynamics  antibacterial activities
基金项目:
作者单位E-mail
付东 黑龙江省科学院高技术研究院 sato2004@163.com 
王珏 黑龙江省科学院高技术研究院  
李鹏 黑龙江省科学院高技术研究院  
黄波 黑龙江省科学院高技术研究院  
谢洋 黑龙江省科学院高技术研究院  
阚侃 黑龙江省科学院高技术研究院 kankan.has@foxmail.com 
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中文摘要:
      以3-甲基吡啶,正溴代烷为原料,通过烷基化反应合成了三种长链N-烷基-3-甲基吡啶溴盐离子液体表面活性剂[Cnmpy][Br] (n:疏水尾链所含碳原子个数,n=12, 14, 16)。采用FT-IR和NMR(1H,13C)对化合物结构进行了表征。采用电导率法和Du Noüy环法测定了表面活性剂的临界胶束浓度(CMC),考察了疏水基链长、温度对胶束行为的影响,并计算了胶束形成过程的热力学参数;研究了所合成表面活性剂对金黄色葡萄球菌(S.aureus)、大肠杆菌(E.colis)和枯草芽孢杆菌(B.subtilis)的抑菌活性。结果表明:298.15 K时,电导率法测得[Cnmpy][Br] (n=12, 14, 16)的CMC分别为9.52,2.32和0.591 mmol/L;Du Noüy环法较电导率法测得CMC小1.21~1.31倍。疏水基尾链碳原子数对CMC的关系符合Stauff-Klevens公式。CMC随着温度的升高,呈现先降低后升高。[Cnmpy][Br]表面活性剂的标准胶束吉布斯自由能和标准胶束化焓均为负值,表明胶束的形成是自发放热过程。抑菌活性实验结果表明,[C14mpy][Br]对3个菌种的抑菌活性最强,抑菌圈直径分别达到为25.0、28.0和26.0 mm。
英文摘要:
      Long-chain ionic liquids surfactants: n-alkyl-3-methylpyridinium bromide [Cnmpy][Br] (n: the carbon numbers of hydrophobic tails, n=12, 14, 16) was synthesized by condensation reaction using 3-methylpyridinium and n-alkyl bromide as raw materials. The ionic liquids surfactants were characterized by FT-IR and NMR (1H, 13C). The critical micelle concentrations (CMC) of surfactants were determined by employing conductometry and Du Noüy ring method. The effects of temperature, carbon chain length on the CMC were also investigated, and the micellization thermodynamic parameters were calculated. The antibacterial activities were screened for compounds against three bacteria. The results showed that the CMC values for [Cnmpy][Br] (n=12, 14, 16) was found to be 9.52, 2.32 and 0.591 mmol/L, respectively. The CMC value measured by Du Noüy ring method were 1.21 to 1.31 times lower than that by conduc-tometry, The relationship between the number of carbon atoms in alkyl chain and CMC value were in ac-cordance with the Stauff-Klevens rule. The variation of CMC values of the compounds with temperature were first decreased and finally increased. The ΔGm and ΔHm values of the [Cnmpy][Br] surfactants were negative indicated spontaneous and radiative nature of the micellization process. The results of antibacterial activities showed that the [C14mpy][Br] surfactants had most intense antibacterial activities against three bacteria. The diameter of inhibition zone was 25.0, 28.0 and 26.0 mm, respectively.
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