Aiming at the characteristics of low-permeability high-temperature and high-salt in Jilin Oilfield, a temperature- and salt-tolerant foaming agent-YUDP suitable for this type of reservoir was developed. The effects of foaming agent concentration, solution mineralization degree, temperature, pH, total content of calcium and magnesium ions, residual oil saturation on the foaming ability of foaming agent, foam stability and oil-water interfacial tension were investigated. The results showed that YUDP was resistant to temperature. 75℃, salt tolerance of 31037.9mg / L, alkali resistance pH = 10, calcium and magnesium ions up to 60mg / L, resistant to residual oil up to 15% crude oil content. Experiments show that YUDP can maintain the oil-water interfacial tension in the order of ?10-2mN/m in the high temperature and high salt environment, achieving the requirement of low interfacial tension flooding. When the mass concentration of YUDP is 0.4%, the foaming volume is up to 250mL, the half-life is 25.7min, the foam strength is 4187.75mL.min, and the oil-water interfacial tension is 0.0261 mN/m to meet the requirements of low interfacial tension foam flooding in Jilin Oilfield.