文章摘要
深共熔溶剂中β-二羰基化合物的α-酰基化
Alpha-Acylation of β-dicarbonyl compounds in deep eutectic solvents
投稿时间:2019-06-21  修订日期:2019-07-23
DOI:
中文关键词: 深共熔溶剂  β-二羰基化合物  α-酰基化反应  绿色合成
英文关键词: deep eutectic solvent  beta-two carbonyl compounds  α-acylation reaction  green synthesis
基金项目:
作者单位E-mail
冯柏成 青岛科技大学 fbc515@163.com 
葛平宇 青岛科技大学  
侯喜超 青岛科技大学  
金岩 青岛科技大学 qaz309@126.com 
摘要点击次数: 34
全文下载次数: 0
中文摘要:
      摘要:以苯甲酰氯衍生物和β-二羰基化合物为原料,在深共熔溶剂中,进行了一系列β-二羰基化合物的α-酰基化反应,对反应机理进行了探究,考察了反应温度、反应时间、深共熔溶剂种类、用量对产物收率的影响。在摩尔分数10%的氯化胆碱/氯化锌深共熔溶剂中,于120 ℃下反应4 h获得最佳收率,为86%~94%。深共熔溶剂回收利用4次后,依然能保持较高的催化活性。该工艺反应条件绿色、温和。
英文摘要:
      Abstract: α-acylation reactions of a series of β-dicarbonyl compounds were carried out in a deep eutectic solvent (DES) using benzoyl chloride derivatives and β-dicarbonyl compounds as raw materials, the catalytic mechanism for the reaction was investigated. The effects of reaction temperature, time, types and the amounts of DES on the product yields were investigated. The best yield can be obtained by reacting at 120℃ for 4 h in 10% mol deep eutectic solvent composed of choline chloride and Zinc chloride, the yield can reach 86%-94%. DES still maintained high catalytic activity after reused 4 times. The reaction conditions of the process were green and mild.
View Fulltext   查看/发表评论  下载PDF阅读器
关闭