Chemical gas sensors are significant in effective and real-time monitoring of harmful acidic gas. However, there are still some problems in sensitivity, selectivity and stability of traditional materials. Metal organic frameworks (MOFs) are a kind of organic-inorganic hybrid materials with porous structure, which have become a hotspot in the research of new functional materials due to their rich porosity structure, adjustable pore structure and large specific surface area. The excellent characteristics of MOFs provide a good idea and direction to solve the above problems. The selectivity and sensitivity of chemical gas sensors can be improved by introducing MOFs or various nanomaterials derived from MOFs on the sensing layer. The sensing performances of chemical gas sensors based on MOFs in recent years are reviewed, and its future development is prospected.