13X zeolite films on α-Al2O3 ceramic tube were prepared by using the method of pre-coating sol, then drying in lower temperature and crystallizing in synthetic solution. The optimal molar composition of synthetic solution was n(Al2O3):n(SiO2):n(Na2O):n(H2O)=1:3.5:7.88:630, and the influences of preparation conditions on formation of 13X zeolite films were investigated. The results showed that continuous and uniform films were observed on α-Al2O3 ceramic tube only with pre-coating sol. It was easier to form continuous films with pre-coating sol than with pre-coating gel. Under the condition that drying temperature and drying time of the pre-coating sol were within 35~45℃ and within 12~18h respectively, continuous 13X zeolite films were easier grown on the surface of ceramic tube judging from XRD patterns and SEM images. By application of the 13X zeolite film to remove lead and cadmium in Salvia miltiorrhiza extract, the removal ratios of lead and cadmium were 86.7% and 44.2% respectively. During the removal process, there was nearly no significant change of active ingredients in Salvia miltiorrhiza extract compared with 13X zeolite particles. The retention rates of solid content, Salvia miltiorrhizanolic Acid B and Rosmarinci Acid were 99.6%, 96.8% and 99.3% respectively. In addition, HPLC fingerprint similarity of Salvia miltiorrhiza extract approached 100% before and after lead and cadmium removing process.