The capsicum resin was used as raw material during the adsorption experiments, and the optimal technology and mechanism of capsaicin adsorption on the 201×7 anion exchange resin was determined by the method of static adsorption. The concentration of capsaicin was detected by visible spectrophotometry, and the adsorption isotherms at the different pH were obtained. The kinetics model of capsaicin adsorption by ion exchange was also established. Experimental results indicated that the optimal pH of capsaicin adsorption was 5.5, and the Langmuir equation was more suitable for the adsorption process when the pH was lower than 5.0 or higher than 6.0; the adsorption isotherms of capsaicin were in highly accordance with Freundlich equation when the pH ranged between 5.0 and 6.0. Under the optimal pH=5.5 and 308.15K, larger mass concentration of the capsicum resin would increase ion exchange speed significantly, and the stirring speed within 800r/min ~ 1200r/min can favor the adsorption process at the initial stage (<30min). By calculation, the adsorption rate constant, activation energy and reaction order were 2.11×10-3s-1, 12.6 kJ/mol and 0.268, respectively, and the kinetics equation of capsaicin adsorption on anion exchange resin was achieved under the optimal pH=5.5 through the solution of Freundlich model.