Using phthalic anhydride (PA) and diethylenetriamine (DETA) as raw materials, electrophilic addition-elimination of the synthetic organic intermediate bis(2-phthalimide)amine (DETA-2PA), Synthesis of a new organic intermediate N,N-bis(2-(1,3-dioxoisoindol-2-yl)ethyl)acrylamide (AC-DETA) by amidation reaction with acryloyl chloride (AC) -2PA). The structure and properties of the product were characterized by FT-IR, 1H-NMR, TGA, fluorescence spectroscopy and elemental analysis. The effects of reaction temperature, reaction time and material ratio (DETA-2PA): (AC) and catalyst dosage on the amine value of synthetic AC-DETA-2PA were investigated. The synthesis process of AC-DETA-2PA was optimized by response surface design, and the preferred synthesis conditions were as follows: n(AC-DETA): n(AC)=1:1.6, reaction temperature was 25?C, catalyst dosage 0.384 g, reaction time 4h, under this condition, the amine value of AC-DETA-2PA can reach 2.96mgKOH/g.