微波辅助离子液体液-液微萃取分析水溶性化妆品中防腐剂的含量
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Determination of three parabens by microwave-assisted ionic liquid dispersive liquid-liquid microextraction in water solubility cosmetic samples
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    摘要:

    本文采用微波辅助离子液体分散液-液微萃取对水溶性化妆品中的对羟基苯甲酸酯类防腐剂进行预处理,并结合高效液相色谱-紫外检测对其分析。论文研究了离子液体用量、分散剂种类及用量、微波时间、萃取时间、离心时间和盐效应对离子液体微萃取效果的影响。在最佳实验条件下,三种酯的富集因数为68.3~124.5,回收率为 55.5~99.2%。标准曲线在 0.1~50 mg/L线性相关,线性相关系数r>0.9989,相对标准偏差(RSD, n=3)为 4.9~5.1%。三种物质的检测限为0.6~1.2μg/L方法操作简单,减少了挥发性有机溶剂的使用,可用于水溶性化妆品和实际水样中防腐剂的检测。

    Abstract:

    Microwave-assisted ionic liquid dispersive liquid-liquid microextraction was developed for the determination of three P–hydroxybenzoic easters (parabens). High-performance liquid chromatography coupled with UV detector was used for the determination of parabens. Several important parameters influencing the extraction efficiency such as volume of extraction solvent , disperser solvent, microwave time, centrifugation time and salt effect, were investigated. Under the optimized conditions, the enrichment factors(68.3~124.5).and accepted recoveries (55.5~99.2%) were obtained for the extraction of the target analytes .The calibration curve was linear with correlation coefficient ranged from 0.9989 to 0.9991 in the concentration level of 0.1~50 mg/L and the relative standard deviations(RSD, n = 3) were 4.9~5.1%. The limits of detection for three parabens were 0.6~1.2μg/L This method minimized the use of organic solvents and was successfully applied to the extraction of parabens from water solubility cosmetic samples and real water samples.

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成敏敏,陈晓青,蒋新宇,张惠.微波辅助离子液体液-液微萃取分析水溶性化妆品中防腐剂的含量[J].精细化工,2011,28(6):

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  • 收稿日期:2010-12-09
  • 最后修改日期:2011-01-13
  • 录用日期:2011-02-22
  • 在线发布日期: 2011-05-09
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