Resveratrol was synthesized from 3,5-dimethoxylbenzaldehyde and 4-methoxylbenzylalcohol by thioetherification, sulphone and Ramberg-B鋍klund Reaction. The effect of different conditions on oxidation yield of thioether and Ramberg-B鋍klund reaction were discussed. The resveratrol totle yield reach to 53.94% by the synthetic routine