The oxidation of cyclohexane catalyzed by N-hydroxyphthalimide(NHPI) and cobalt sulphonated phthalocyanine(CoSPc) was investigated, in which GC was used to analyze the composition of oxidation products, except the normal products cyclohexanone and cyclohexanol, cyclohexanol acetate was fond and verified, according to standard sample. The effect of reaction time, temperature, the amount of NHPI and/or CoSPc were examined, the optimal reaction conditions of cyclohexane oxidation were as follows: reaction time 2 h, reaction temperature 80℃, n(Cyclohexane) : n(NHPI) = 10:1, n(NHPI) : n(CoSPc) = 6:1. Under the optimal conditions, the 10.5% yield of cyclohexanone, 1.1% of cyclohexanol and 0.4% of cyclohexanol acetate were gotten, and the total yield reached 12.0%.