Tobacco polysaccharide was extracted by ultrasonic extraction. Based on the single factor experiment , the conditions of phosphorylated tobacco polysaccharide were optimized with response surface methodology. The effects of phosphorylated tobacco polysaccharide, tobacco polysaccharides, distilled water, and propylene glycol on the moisturizing capacity of cut tobacco were studied, respectively，Finally, the sensory quality of tobacco leaf polysaccharides and phosphorylated tobacco leaf polysaccharides were tested. The results showed that the phosphate mass fraction reached 11.68% under the pH=9.0, the reaction time of 6.1 hours, and the temperature of 95 ℃. The moisturizing capacity was phosphorylated tobacco polysaccharide > tobacco leaf polysaccharide> propylene glycol> distilled water. The sensory evaluation results showed that the addition of phosphorylated tobacco leaf polysaccharide had a significant effect on improving cigarette smoking quality.