A series of anti-corrosion nanomaterials, AcOH-PANI, AcOH-PmAP, MOPAc-PmAP and MOPAc-PANI were synthesized by using aniline (AN) and m-aminophenol (mAP) as monomers, acetic acid (AcOH) and p-methoxyphenylacetic acid (MOPAc) as doped acids, Fenton (Fe2+/H2O2) reagent as initiator. The morphology and structure of the polymer materials were characterized by FTIR, UV-vis, XRD, SEM and particle size analyzer. The results showed that the polymer prepared by using p-methoxyphenylacetic acid as doped acid had uniform particle size distribution and good solubility. Electrochemical tests suggested that the polymer was a cathode-based mixed corrosion inhibitor, and the corrosion inhibition efficiency followed the order MOPAc-PmAP > AcOH-PmAP > MOPAc-PANI > AcOH-PANI. MOPAc-PmAP and AcOH-PmAP, in presence of Tween80, showed better anticorrosion properties. Especially when the concentration of corrosion inhibitor was 100 mg/L and that of Tween80 was 50 mg/L, the system of MOPAc-PmAP-Tween80 had the outstanding corrosion inhibition efficiency as high as 96.05%, which was higher than the system in absence of Tween80 (71.04%), indicating that there was excellent synergism between MOPAc-PmAP and Tween80.