Anthocyanins wasrecovered by two-step method using DESs to extract, macroporous resin to separate, and mulberry pomace as raw materials. The effect of different types of DESs and extraction methods on the extraction efficiency of anthocyanins was tested by extraction experiments. The anthocyanins were recovered, DESs was removed, and anthocyanins were recovered by using macroporous resin of different types as adsorption carrier. HPLC and HPLC-MS were used to quantify and characterize anthocyanins. As a result, oxalic acid-choline chloride stood out as the best DES for extraction, with an excellent yield efficiency of 97.49%, and macroporous resin X-5 was the best absorbent for the desolvation of NADESs, with a high recovery of 92.76%.