As one of the major greenhouse gases, CO2 has caused a series of environmental problems, such as global warming. CO2 conversion to valuable products is of great significance to alleviating global climate issues. Methanol is not only a high energy fuel but an important chemical intermediate. CO2 hydrogenation to methanol is a feasible way to realize CO2 recycling. However, at present, there are a series of problems such as low selectivity, low CO2 conversion rate and low methanol synthesis rate. Thus, the development of efficient and highly selective catalysts is critical to realize the industrial application of CO2 hydrogenation to methanol. In recent years, metal-organic framework (MOFs) materials have attracted extensive attention in the field of catalysis due to their structural diversity and design flexibility. In this paper, we reviewed the advantages, synthesis methods and research progress of MOFs catalysts in the field of CO2 hydrogenation to methanol. Furthermore, the challenges and prospects of the application of MOFs catalysts in this field were also discussed.