Preparation of Co and Mn catalysts suitable for the oxidation of paramenan by hydrothermal synthesis, the catalysts were characterized by N2 adsorption-desorption, SEM， XRD, FTIR, XPS, the catalytic effect of the catalysts in the oxidation of p-menthane was explored. The continuous production process of bubbling column reactor is used to carry out the oxidation reaction of p-menthane to generate p-menthane hydroperoxide; the reaction process is explored from the aspects of type of catalyst, reaction temperature, reaction time, and whether to add an initiator before the reaction. The optimum process conditions were as follows: adding PMHP initiator and Co catalyst before the reaction, the reaction temperature was 120°C, and the reaction time was 8h; According to GC-MS analysis, the content of p-menthane hydroperoxide was 30.28%, which reached an excellent level in the market.