β-丙氨酸的生物代谢过程及生物法制备研究进展
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南京林业大学 轻工与食品学院

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南京林业大学青年拔尖人才项目(GXL2018010),江苏省高校优秀中青年教师和校长境外研修计划项目


Progress in research on the biometabolic pathways and biopreparation of β-alanine
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College of Light Industry and Food Engineering,Nanjing Forestry University

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    摘要:

    β-丙氨酸是自然界中唯一一种天然存在的β-型氨基酸,也是一种非蛋白氨基酸。β-丙氨酸在食品工业、医药工业、化工业和饲料工业等领域具有重要用途,市场前景非常广阔。目前,β-丙氨酸合成方法有化学合成法和生物合成法。相较于化学法复杂的生产流程,生物法具有产物专一、条件温和及工艺简单等优点,是目前公认的更环保、更有前景的β-丙氨酸生产方法。本文综述了β-丙氨酸的性质、应用、生物代谢过程及目前主要的生物制备方法,重点讨论了生物法生产β-丙氨酸的现状及存在的问题。以期为β-丙氨酸的高效、绿色生产工艺开发及工业化应用提供参考。

    Abstract:

    β-Alanine is the only naturally occurring β-type amino acid in nature, and it is also a non-protein amino acid. β-Alanine has important applications in the food industry, pharmaceutical industry, chemical industry, feed industry, and other fields, and its market prospect is very broad. At present, β-Alanine synthesis methods include chemical synthesis and biosynthesis. Compared with the complex production process of the chemical method, the biological method has the advantages of product specificity, mild conditions, and simple process. At present, it is recognized as a more environmentally friendly and promising β-alanine production method. This paper reviews the properties, applications, biological metabolic processes and main biological preparation methods of β-alanine, and focuses on the current situation and existing problems of biological production of β-alanine. It is expected to provide reference for the development of efficient and green production process and industrial application of β-alanine in the future.

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丁乾,段绪果.β-丙氨酸的生物代谢过程及生物法制备研究进展[J].精细化工,2023,40(4):

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历史
  • 收稿日期:2022-07-18
  • 最后修改日期:2022-10-21
  • 录用日期:2022-10-24
  • 在线发布日期: 2023-02-17
  • 出版日期: 2022-09-30