1.School of Light Industry,Beijing Technology and Business University;2.School of Light Industry,Beijing Technology Business University
3-噻唑啉是一类含硫含氮的杂环香料化合物,本论文以脂肪醛、2,5-二甲基-2,5-二羟基-1,4-二噻烷和氨水为原料,水或乙醇为溶剂,合成了4-甲基-3-噻唑啉、2,4-二甲基-3-噻唑啉、2-乙基-4-甲基-3-噻唑啉、2-异丙基-4-甲基-3-噻唑啉、2-丙基-4-甲基-3-噻唑啉、2-丁基-4-甲基-3-噻唑啉六种4-甲基-3-噻唑啉类香料化合物,它们的产率为为50%-91%,通过质谱、1H NMR和13C NMR对它们的结构进行表征；并且对合成的六种4-甲基-3-噻唑啉类香料化合物的香气特征进行了评价,对保留指数进行了测定,结果表明它们都具有烤香、坚果香和焦香,它们在HP-INNOWAX极性色谱柱上的保留指数范围是1398-1686,在HP-5MS非极性色谱柱上的保留指数范围是938-1253。研究结果对4-甲基-3-噻唑啉类香料化合物的生产、应用和鉴别具有重要的参考价值。
3-Thiazoline is a kind of heterocycle flavor compound containing sulfur and nitrogen. Six 4-methyl-3-thiazoline flavor compounds, including 4-methyl-3-thiazoline, 2,4-dimethyl-3- thiazoline, 2-ethyl-4-methyl-3-thiazoline, 2-isopropyl-4- methyl-3-thiazoline, 2- propyl-4- methyl-3-thiazoline and 2- butyl-4- methyl-3-thiazoline, were synthesized by applying fatty aldehydes, 2,5-dimethyl-2,5-dihydroxy-1,4-dithiane and aqueous ammonia as the raw materials and water or ethanol as solvent in this paper; their yields were 50%-91%. Six compounds were identified by mass spectra, 1H NMR and 13C NMR, followed by evaluating their odor characteristics and measuring their retention indices (RI) on two capillary columns with different polarities. The results indicated that six odorants had roast, nutty and burnt odor, and the RI ranges on HP-INNOWAX column and HP-5MS column were 1398-1686 and 938-1253, respectively. The results obtained had important referenceSvalueSforSmanufacturing, applying and identifying 4-methyl-3-thiazoline flavor compounds.