In order to enhanced the oil recovery in high pour point oil reservoir, a microemulsion with high pour point depression and oil displacement performance is mainly prepared with anionic/cationic surfactants (sodium stearyl ether carboxylate and octadecyl trimethyl ammonium bromide) and pour point depressant (mixture of polyacrylates and ethylene-vinyl acetate copolymers). Pour point, phase behavior, solubilizing components analysis, interfacial property, core flooding and a series of tests are carried out to evaluate the performance of the microemulsion. The results show that the microemulsion has good pour point reducing performance and the reduction rate is more than 34%. Phase behavior tests show that the microemulsion has good emulsifying performance, especially for the long chain alkane. The microemulsion can reduce the oil-water interfacial tension to 10-3 mN/m. The field test shows that the maximum water cut of the wells decreased from 94.8% (w) to 89.1% (w), and the maximum daily oil production increased from 4.5 t to 7.7 t, which can achieve a good effect of enhanced oil recovery.