Explore the synergistic antioxidant capacity of Lingonberries anthocyanin and Lonicera japonica polyphenols. Determination of single component and compound (respectively compounded with Lingonberries anthocyanin and Lonicera japonica polyphenol mass ratio 5:1, 2:1, 1:1, 1:2, 1:5) on DPPH free radical, ABTS free radical, hydroxyl radicals, superoxide anion scavenging ability, copper ion reducing ability and total reduction reaction, calculate the combination index CI, and analyze whether the compound in each proportion has a synergistic antioxidant effect. The results showed that, except the compound (1:5) showed antagonistic effect on scavenging DPPH free radical, the other proportion compound showed synergistic effect in each index. Among them, when the DPPH radical scavenging rate and copper ion reduction capacity of the complex (2:1) reached 50%, CIDPPH=0.59±0.07 and CI copper ion =0.35±0.03, indicating that the complex with mass ratio of 2:1 had a synergistic effect on the scavenging of free radicals and a synergistic antioxidant effect. When the effect of complex (1:1) on ABTS free radical and total reduction was 50%, CIABTS=0.58±0.04, and CI total reduction force =0.33±0.04, indicating that the antioxidant capacity was significantly improved after 1:1 combination. The experiment proved that the combination of Lingonberries anthocyanin and Lonicera japonica polyphenols have synergistic effect on the free radical scavenging and metal ion reduction ability. The results of the study show that the combination of Lingonberry anthocyanin and Lonicera japonica polyphenol has a strong antioxidant synergistic effect, which can balance the cold of honeysuckle, relieve the current situation of large amount of honeysuckle and short supply. It provides a theoretical basis for the utilization and development of natural green and safe antioxidant health products.