文章摘要
孙君颖,卢莉璟,卢立新,林自东.基于迷迭香精油温敏脂质体的温度响应型控释抗氧化复合膜制备[J].精细化工,2021,(8):0
基于迷迭香精油温敏脂质体的温度响应型控释抗氧化复合膜制备
Preparation of temperature-responsive controlled-release antioxidant composite membrane based on temperature-sensitive liposomes of rosemary essential oil
投稿时间:2021-02-20  修订日期:2021-03-24
DOI:
中文关键词: 温敏脂质体,温度敏感,普鲁兰多糖,壳聚糖,抗氧化,功能材料
英文关键词: temperature sensitive liposome,temperature sensitive,pullulan,chitosan,antioxidant,functional materials
基金项目:国家重点研发计划资助项目(2016YFD0400701)
作者单位E-mail
孙君颖 江南大学 1060959004@qq.com 
卢莉璟 江南大学  
卢立新 江南大学 lulx@jiangnan.edu.cn 
林自东 山东碧海包装材料有限公司  
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中文摘要:
      以合成磷脂DPPC和胆固醇为膜材,采用乙醚注入法制备迷迭香精油温敏脂质体,将温敏脂质体添加到壳聚糖-普鲁兰多糖溶液中,以BOPP为基膜制备抗氧化复合膜。对迷迭香温敏脂质体进行包封率、粒径分布、多分散性指数(PDI)、相变温度和原子力显微镜的测定,测定薄膜中精油释放速率,验证薄膜温度响应特性。结果表明,制备温敏脂质体平均包封率为65.6%,平均粒径为164.8nm,多分散性指数(PDI)平均值为0.163,相变温度为38.5℃和41.8℃。抗氧化复合膜在42℃条件下7天内释放量为94.1%,具有显著的温度响应控制释放作用。
英文摘要:
      Using synthetic phospholipid DPPC and cholesterol as membrane materials, the rosemary essential oil (REO) temperature-sensitive liposomes (t-L) were prepared by ether injection method, The temperature-sensitive liposomes were added to the chitosan-pululan solution, and BOPP was used as the base membrane to prepare an antioxidant composite membrane. The encapsulation efficiency, particle size distribution, PDI dispersion coefficient, phase transition temperature and atomic force microscopy of rosemary temperature-sensitive liposomes were measured. Measure the release rate of essential oil in the film to verify the temperature response characteristics of the film. The results showed that the average encapsulation efficiency of the prepared temperature-sensitive liposomes was 65.6%, the average particle size was 164.8nm, the average polydispersity index (PDI) was 0.163, and the switching temperature was 38.5℃ and 41.8℃. The anti-oxidant composite film released 94.1% in 7 days at 42℃, it has a significant temperature response control release effect.
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