To prepare PPLA polymeric micelle and investigate their general properties, in vitro drug release characteristics. The surface hydrophilicity investigated by static water contact angle method. Using rotary evaporation method for reparation graft copolymer micelles. Critical micelle concentration(CMC), diameter, morphology and surface potential of the micelles were investigated by pyrene fluorescent probe technique,inverted imaging microscope and dynamic light scattering (DLS), respectively. Single factor tests and orthogonal tests on the the ratio of acetone, addition amount and addition sequence of material and drug were carried out for optimization. The in vitro release behavior of naproxen from polymeric micelles was investigated using dialysis method .The results indicated the water contact angle of the PPLA film was nearly 5? CMC was 3?0-4g?L-1. The micelle was globular-shaped ，had a narrow size distribution with an average particle size under of 200nm,the Zeta potential was lower than-20 mV, while dilution, standing and alkaline change to basic condition had no effect after preparation. The optimum preparation conditions were 0.8mg naproxen,10mgPPLA simultaneous dissolution in 1.0ml acetone，then drop into 10ml water. In PBS(0.01 mol?L-1)at 37℃ can duration release be up to 5 days. So we can concluded that PPLA would be a noveles applied Polymer Carriers as promising drug delivery system for hydrophobic drugs.