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以实际刊发为准
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FENG Zhaoyuan, WANG Yisen, WANG Zhenyu, DONG Zhe, FAN Ziluan, ZHANG Hua
2024,41(11), DOI:
Abstract:
Plant polysaccharides are widely present in nature and have various biological activities, including immune regulation, antioxidant, anti-tumor, etc. Due to its low toxicity and easy absorption, it’s currently a hot research topic in the fields of medicine and food science. However, low activity hinders its widespread application. The synergistic reaction between plant polysaccharides and active ingredients can exert their biological activity through multiple targets and pathways, achieving a 1+1 ≥ 2 effect. Recently, there has been an increasing amount of research on the biological activity of polysaccharides, but there is limited review on the cooperative effects of polysaccharides with other active ingredients. This article summarizes research reports on the cooperative effects of polysaccharides both domestically and internationally, and reviews the cooperative effects and mechanisms of polysaccharides and active ingredients in six aspects: antioxidant, antibacterial, hypoglycemic, anticancer, anti obesity, and liver injury inhibition. The aim is to provide reference for
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JIANG Rui, DUO Yong-chao, ZHANG Shu-lin, JIN Xin, QIAN Xiao-ming, WANG Wen-yu
2024,41(11), DOI:
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The latest research progress of piezoelectric energy harvesters and their use in the field of human energy harvesting has been summarized, including the design of piezoelectric energy harvesters for human energy harvesting, the selection of piezoelectric materials more suitable for wearable or implantable applications, and the improvement of the performance of piezoelectric energy harvesters for the human body by new processes. Nowadays, as traditional energy sources are becoming increasingly scarce, higher requirements for environmentally friendly energy harvesters and self-powered wearable devices are being put forward by people, and future piezoelectric energy harvesters for the human body will face more opportunities and challenges. The development and progress of new materials, new technologies, and new processes should be focused on to promote the development of piezoelectric energy harvesters, so as to make them better adapted to different applications and to improve the efficiency of energy harvesting from the human body.
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ZHANG Huiming, DENG Ziyi, XHEN Chen, WANG Shuaihao, LIU Zhiyao, XU Qiong
2024,41(11), DOI:
Abstract:
The preparation of fuel chemicals using biomass as raw materials is of great significance in reducing dependence on fossil fuels and building a green energy structure. In recent years, research on the one-pot multi-step conversion of the biomass platform compound furfural into high value-added fuel chemicals such as levulinic acid and levulinate esters, γ-valerolactone and 2-methylfuran has attracted attention. In this paper, the research progress in bifunctional catalysts for one pot conversion of furfural to levulinic acid, levulinic acid ester, γ-valerolactone and 2-methylfuranin in recent six years is reviewed. The reaction paths and possible mechanisms of the multi-step conversion reactions were summarized, and the types of high-efficiency catalysts and the required active centers for each step were also summarized. It provides a new idea for the design and preparation of high efficient bifunctional catalysts for the conversion of furfural into high-value fuel compounds , and provides valuable reference for further development and better utilization of furfural.
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WANG Guixia, WANG Jiawei, WANG Cai Yao, ZHANG Xin Yu, ZHOU Chao, KONG Xiangfei
2024,41(11), DOI:
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The structure of small organic molecules with self-assembly characteristics is generally composed of three parts: one end of the molecule is the anchor group, the other end is the tail group that regulates the performance, and the middle is connected by a backbone. Such molecules usually use silanes, thiols, acids, etc. as anchor groups; The tail group is generally composed of an electron-withdrawing group or an electron-donor group; The backbone is generally composed of alkyl or aromatic chains of different lengths. This article presents an overview of the attributes and properties exhibited by these self-assembling molecular architectures over the past decade and summarizes their applications in optoelectronics, biomedical science, sensing, and corrosion prevention domains. By comparing the advantages and disadvantages of such molecular self-assembly film-forming modified devices, the structure-activity relationship is summarized, and some assumptions are put forward for such molecules in combination with the research of our group.
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YANG Panpan, YANG Jianjun, WU Qingyun, WU Mingyuan, ZHANG Jian''an, LIU Jiuyi
2024,41(11), DOI:
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Hydrogel is a polymer material formed by hydrophilic polymer chain with 3 D network structure and with strong water absorption and water retention; starch is an environmentally friendly natural polysaccharide. The starch-based hydrogel prepared with starch as the substrate has good biocompatibility, strong biodegradability, and excellent solvent absorption capacity. This paper first briefly describes the common starch modification methods, including physical modification, chemical modification, enzyme modification and compound modification. Then the preparation and application of starch-based hydrogel: the preparation method of starch-based hydrogel includes chemical cross-linking, reversible physical cross-linking; it has been widely used in biological sensors, medical dressings, drug transport carriers, tissue engineering stents, agricultural soil protection, how to improve the functionality of starch-based hydrogel. Finally, the development direction of starch-based hydrogel, such as the green development of crosslinking agents and initiators, the introduction of dual network, and the expansion of composite functions such as conductivity and antibacterial, is discussed.
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ZHAO Xiaonan, ZUO Shixiang, CHEN Jieyi, SUN Xuzhang, ZHANG Renzhi, YAO Chao, GUI Haoguan
2024,41(11), DOI:
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Adsorption is an efficient strategy to remove volatile organic compound (VOC) pollutants. Herein, a series of cyclodextrin-based porous materials (CD-PMs) were fabricated from a dimethylsulfoxide (DMSO)-in-paraffin oil high internal phase emulsion (HIPE) through the step-growth polymerization. Morphologies and rheological behaviors of the original HIPEs were controlled by cyclodextrin’s types and contents. Subsequently, the apparent density, porous structure, and pore throat of the corresponding CD-PMs were variegated under a similar law. The resultant CD-PMs exhibited robust mechanical properties and high adsorption capacities of various VOCs, i.e., toluene and acetaldehyde. Moreover, CD-PMs removed the toluene through a physical adsorption process which could keep a high absorption capacity even after reused for 10 cycles. In the case of acetaldehyde, the CD-PMs absorbed it via chemical adsorption, resulting in a remarkable absorption capacity. These CD-PMs are perfect VOCs adsorbents from renewable resources, meeting the sustainable development.
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LIU Yuanqian, CHEN Yingbo, XU Linzhe, TAO Keyu, LU Xun, WANG Xiaozhe
2024,41(11), DOI:
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In order to improve the defects of the ultrafiltration membrane prepared by blending UiO66 particles with polyether sulfone (PES), such as poor anti-fouling ability and weak interaction between particles and membrane, a novel ultrafiltration membrane was obtained by phase inversion of PES polymer dopes containing modified UiO66 particles. The modified UiO66 particles (UiO66-NH2 and PVP-UiO66-NH2) was obtained by solvothermal method through introducing amino groups and polypyrrolidone (PVP) onto UiO66 by replacing ligands. The effects of types and contents of particles on pure water flux, retention rate, anti-fouling ability, long-term stability, hydrophilicity and mechanical properties of PES blending ultrafiltration membranes were investigated. The results show that the water flux of the blending membrane with 2.5 wt% PVP-UiO66-NH2 reaches to 506.9 L/(m2·h), which is doubled compared to the original membrane. The tensile strength is about 3.06 MPa, and the flux recovery rate is 95.97% after simple water washing after BSA contamination. The water flux can be maintained at about 300 L/(m2·h) for long-term filtration. The novel ultrafiltration membrane not only has enhanced pure water flux, but also has excellent anti-fouling ability and stability, suggesting a high application prospect.
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ZONG YiChao, ZHANG FuQing, GUO LiRui, YUAN Jun
2024,41(11), DOI:
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In this paper, zinc oxide quantum dots (ZnO QDs) were synthesized using the sol-gel method, and loaded onto cerium oxide microspheres (CeO2) through an impregnation process, resulting in the preparation of ZnO QDs modified cerium oxide binary composite material (ZnO QDs/CeO2). The structure and morphology of the composite material were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM), and other methods. The efficiency of the degradation of rhodamine B was tested under visible light, and the photoelectrical performance of the composite material was characterized using EIS、UV-vis. The experimental results are as follows: the diameter of ZnO QDs was 6-9 nm, the diameter of CeO2 microspheres was 800 nm, and ZnO QDs were uniformly distributed on the surface of CeO2, extending the light response range of the composite material to 550 nm. The efficiency of the ZnO QDs/CeO2 composite for the degradation of rhodamine B under visible light was twice that of CeO2. Through the study of the constitutive relationship, it was found that the introduction of ZnO QDs led to an increase in the light absorption range of the composite material and an improvement in the efficiency of photoinduced electron-hole separation, demonstrating outstanding photocatalytic performance.
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chenzuoyi, chenkaochang, lihuahui, keyongxia, liuxiaojun, ZHAO Dan-hua
2024,41(11), DOI:
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The biological carbon (COSBC) was prepared with camellia oleifera shell (COS) as raw material.and it was uniformly dispersed into sodium alginate gel solution to form a mixed gel solution. The composite calcium alginate gel microspheres (CA/COSBC) were prepared with ball drop method through the mixed gel solution as matrix precursor dripping into CaCl2 solution for cross-linking action between Ca2+ and sodium alginate. The results indicated that the optimum conditions for the preparation of CA/COSBC microspheres were as follows: the mass ratio of sodium alginate (2%) to COSBC was 4 : 1, 2 % CaCl2 as coagulation bath, and the curing time was 60 min. The morphological structure of CA/COSBC was characterized by SEM and FTIR spectrum. The effects of CA/COSBC dosage, solution pH and temperature, initial concentration of Pb(II), and adsorption time on the adsorption effect of Pb(II) in wastewater were investigated in detail, and the thermodynamic and kinetic behavior of CA/COSBC adsorption for Pb(II) were explored. The results showed that the removal rate of Pb (II) in wastewater was as high as 72.81 % under the conditions of room temperature, pH 5 and 250 mg/L Pb (II) solution, adsorbent dosage of 0.77 g/L and contact time 4 h. The adsorption capacity of CA/COSBC for Pb (II) was 236.4 mg/g. The adsorption process was spontaneous and conformed to the Freundlich thermodynamic model and the pseudo-second-order kinetic model. The results showed that the chemical adsorption of the multi-molecular layer played a dominant role. In addition, intraparticle diffusion is not the only factor controlling the adsorption process, and surface adsorption and boundary layer diffusion can also affect it.
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ZENG Wujun, ZENG Bin, PENG Qiao, NING Xutao, ZHANG Min
2024,41(11), DOI:
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Using Cetyltrimethylammonium Bromide (CTAB) as template and bromine source ?by adding MXene (Ti3C2), Ag3PO4-decorated AgBr nanowires/Ti3C2 (Ag3PO4-AgBr NW/Ti3C2) composites were synthesized by co-precipitation method. The microstructure, crystal structure, elemental composition, optical absorption and photocarrier recombination of Ag3PO4-AgBr NW/Ti3C2 were characterized by SEM, TEM, XRD, XPS, uv-vis diffuse reflectance spectra and fluorescence spectra. The effect of 1% Ti3C2 dispersion on the photocatalytic degradation of Rhodamine B (RhB) by Ag3PO4-AgBr NW/Ti3C2 was investigated. The results showed that the layered-shaped Ti3C2 were dispersed around AgBr nanowires and Ag3PO4 nanoparticles decorated them, thus forming the double-heterostructure of Z-scheme and Schottky. Ag3PO4-AgBr NW/Ti3C2-5 prepared by adding 0.5 g Ti3C2 dispersion with 1% mass fraction had the best performance of photocatalytic degradation of RhB. The photocatalytic degradation rate of RhB (30 mL, 10 mg/l) was 94.4% by Ag3PO4-AgBr NW/Ti3C2-5 (30 mg). The ·OH radicals and ·O2? was the main active species in the photocatalytic degradation of RhB by Ag3PO4-AgBr NW/Ti3C2. The Z-type and Schottky double heterojunction formed between AgBr, Ag3PO4 and Ti3C2 promoted the separation efficiency of photogenerated electron-hole pairs (e-h+) and enhanced the photocatalytic performance of Ag3PO4-AgBr NW/Ti3C2.
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YANG Wen-ju, TANG Yu-xia, CHEN Wei-qi, WANG Hua, WANG HAO
2024,41(11), DOI:
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Dopamine (DA) was self-polymerized under air and TEMPO conditions to form A-PDA and T-PDA, respectively, and mixed with sodium carboxymethyl cellulose (CMC), respectively, and vanillin was used as a cross-linking agent to prepare CA-P and CT-P aerogels, and composite phase change materials were obtained PEG2000 vacuum impregnation. SEM, FTIR, DSC, TG and infrared thermal imagers were used to characterize and analyze the microscopic morphology, chemical structure, thermal stability and photothermal conversion performance of aerogels. The results showed that CMC, CA-P and CT-P aerogels had good encapsulation stability against PEG2000. The addition of PDA improved the photothermal conversion efficiency of the composite phase change materials, in which PEG/CA-P reached 51.75%, while PEG/CT-P reached 76.27%. Compared with PEG/CMC and PEG/CA-P, the enthalpy of phase change of PEG/CT-P composites is closer to that of pure PEG2000, about 97%,and the energy storage effect is better. The three composite phase change materials exhibited excellent cycling stability.
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ZHAO Ming-ming, BAO Jun-jie, HUANG Yi-ping
2024,41(11), DOI:
Abstract:
A series of CO2 based polyurethane acrylate UV cured resins (PUA) were prepared using CO2 based poly(propylene carbonate) diol (PPCD), dicyclohexylmethane diisocyanate (HMDI), hydroxypropyl methacrylate (HPMA), 2,4,6-trimethylbenzoyl-dimethylphenyl phosphine oxide (TMO) and other materials. The structure and properties of UV cured resin were analyzed through tests such as FTIR, XRD, mechanics, TG and viscosity. The results showed that as the molar ratio n(- NCO):n(- OH) of isocyanates in HMDI to hydroxyl groups in PPCD increased, the contact angle, hardness and tensile strength of the PUA membrane increased, while the resin viscosity, film water absorption and elongation at break decreased. When the n(- NCO):n(- OH) was 2:1, the UV curable resin (PUA-4) showed the best comprehensive performance with the film tensile strength of 32.9 MPa and elongation at break of 139.2%. The contact angle of the film was 86.9°, the 24h water absorption was 8.20% and the Shore hardness was 94HA.
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MA Ziyang, WANG Shuai, CAO Hu, WU Qinyu, MA Yangzhou, SONG Guangsheng
2024,41(11), DOI:
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Silicon material is the most promising high energy density anode material because its specific capacity (4200 mA h/g) is more than 10 times higher than that of commercial graphite anode (372 mA h/g). However, the huge volume change of silicon anode materials during charging and discharging, resulting in irreversible capacity loss and low initial coulombic efficiency, makes the practical application of silicon anode limited. In order to reduce the volume change effect, in this research, micron Si and nano-amorphous SiO2 (Nano-SiO2) were synthesised by sand milling with anhydrous ethanol as the abrasive agent to form micro-nano Si/SiO2 composites (SNSO), and nano-Fe2O3 was introduced to prepare Fe2O3-modified Si/SiO2 composites (SNSO@Fe2O3) by mechanical ball milling. XRD, XPS, SEM and TEM were used to characterise the modified composites and test their electrochemical properties. The results show that SNSO and Fe2O3 present a regular spherical core-shell structure with an amorphous layer in the outer shell under the action of high-energy ball milling, and the modified samples exhibit excellent cycling performance, with the reversible specific capacity remaining stable above 986 mA h/g after 100 cycles at a current density of 110 mA/g, which is an enhancement of about 43% compared with that of SNSO. Its stable cycling performance is attributed to the generation of FeSi phase during ball milling and the amorphous layer shell structure formed on the Si surface by the in-situ reaction of amorphous SiOx and Fe2O3, which effectively mitigates the volume expansion of Si.
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LI You, ZHANG Yuanyuan, RAN Zhaoming, ZHANG Pingping, LIU Changyao, WANG Ce, XU Baocai
2024,41(11), DOI:
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Based on a green synthesis method, 9 fatty acyl amino acid surfactants were prepared by reacting methyl laurate, methyl myristate and methyl palmitate with alanine, serine and threonine, respectively. The effects of the synergistic interaction of hydrophilic/hydrophobic groups on the interfacial behavior were investigated by surface/interfacial tension measurement and interfacial dilatational rheological experiments. The results showed that, compared with that of alanine, the hydroxyl groups in the α-substituents of the serine and threonine surfactants contributed to the enhancement of intermolecular hydrogen bonding, the improvement of interfacial activity, and the close arrangement of surfactant molecules at the interface. Meanwhile, the increase of fatty acyl chain length made the effect of amino acid α-substituents on the interfacial properties of surfactants more significant. In turn, the polar α-substituent of amino acid facilitated the hydrophilic-lipophilic balance of long-chain fatty acyl surfactants and improved their interfacial properties. Due to the synergistic effect of hydroxyl group and long chain fatty acyl group, the CMC of palmitoyl serinate surfactant declined to 3.9×10-4 mol/L, the surface tension of aqueous solution was reduced to 27.60 mN/m, the minimum surface area occupied per surfactant molecule at surface decreased to 0.87 nm2, and the interfacial dilatational modulus was enhanced as high as to 47.6 mN/m. Hydroxyl group of amino acid and long fatty acyl group showed a good synergistic effect in enhancing the interfacial properties,.
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LU Longbo, BAO Yihong, WANG Jinling
2024,41(11), DOI:
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In order to realize the high-value utilization of active substances in raspberry stems, 29 varieties of raspberry stems in Northeast China were selected as the research objects; ultrasonic-assisted extraction was employed to derive active substance extracts from raspberry stems, and the contents of total phenols, total flavonoids, phenolic compounds, antioxidant and antibacterial activities were determined, followed by the correlation analysis. The results indicated the contents of total phenols in raspberry stems were 1.10~3.27 g/100g (dried raspberry stem), and total flavonoids were 0.69~1.32 g/100g (dried raspberry stem); where ‘Beijing 32’ showed the highest total phenol contents, and ‘Beijing 21’ showed the highest total flavonoid contents. Ten phenolic acid derivatives and seven flavonols were identified from 29 varieties of raspberry stems, mainly chlorogenic acid, arbutin, cryptochlorogenic acid and ellagic acid, with chlorogenic acid content ranging from 2.51 to 11.38 mg/g (dried raspberry stems). The half inhibitory concentration (IC50) of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH?) and 2,2"-azino-bis(3-ethylbenzthiazoline-6-sulphonate) (ABTS+?) for 29 varieties of raspberry stem extracts ranged from 2.22 to 5.79 g/L, and 1.22 to 4.32 g/L, respectively; and the iron ion reducing capacities ranged from 0.50 to 1.09 mmol/g (dried raspberry stems). The 29 varieties of raspberry stem extracts had inhibitory effects on four foodborne pathogens (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and pseudomonas aeruginosa), and showed the strongest antibacterial ability in pseudomonas aeruginosa, with minimum inhibitory concentration and minimum bactericidal concentration of 3.12 g/L and 6.25 g/L, respectively. The higher polyphenol content in 29 varieties of raspberry stem extracts, the stronger antioxidant capacity and antibacterial activity.
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WANG Yingxia, PAN Liuyi, SU Tao, LI Dong, LI Wenhong
2024,41(11), DOI:
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Selective hydrogenation of acetylene is a key process in the ethylene industry to remove acetylene impurities and obtain high-quality ethylene products. The development of highly active and selective catalyst for acetylene hydrogenation, which are green and economical, is currently a hot and difficult research topic in this field. In this paper, xCeO2-Al2O3 supports with different CeO2 additions were synthesized by hydrothermal method and evaluated experimentally. The results showed that 2Ni/5CeO2-Al2O3 exhibited excellent catalytic performance with 99.7% conversion and 94.9% selectivity at 280℃ compared with the catalyst without CeO2 addition. However, the excess CeO2 would reduce the specific surface area and pore volume of the catalyst, block the catalyst pores, and affect the dispersion of Ni species on the surface, which in turn would affect the reaction performance of the catalyst. The catalyst samples were characterized by XRD, H2-TPR, SEM, BET, XPS, NH3-TPD and TG. The excellent performance was found to be mainly attributed to the addition of CeO2 attenuating the strong Ni-Al interactions and reducing the generation of inert NiAl2O4 spinel phases, which effectively enhanced the activity, selectivity and stability of the catalyst.
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LI Jian, XIA Xin-yu, ZHANG Xi, LIU ZHI-Gang, YANG Li-na
2024,41(11), DOI:
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At the same time, ammonium fluoride solution and lanthanum nitrate solution were added to hydrolyze tetrabutyl titanate, and F-La-co-doped amorphous TiO2, namely F-La-TiO2 (Am), was prepared, and applied to the photocatalytic oxidative desulfurization of simulated diesel fuel with DBT (dibenzothiophene) as the probe. The characterization results of XRD, FT-IR, XPS, UV-vis, SEM, PL and VB-XPS showed that after successful co-doping of F and La, the electronegativity of F narrowed the band gap of the catalyst, and the formation of La-O bonds provided more oxygen vacancies, promoted the formation of impurity energy levels, and effectively inhibited the recombination of electrons. Under the optimized operating conditions, that is, the catalyst dosage is 1 wt% (based on simulated diesel), the O/S molar ratio is 15:1, the agent-oil ratio (v/v) is 1:1, and the desulfurization rate reaches 94.10%, which is 12.71%, 9.52% and 27.5% higher than the amorphous La-TiO2(Am), F-TiO2(Am) and anatase F-La-TiO2(An), respectively. The catalyst was reused four times, and the desulfurization rate could still reach more than 85%, and the mechanism studies showed that the main active intermediate species were superoxide radicals (· O2-) and holes (h+).
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CHEN lin, TONG Xing-xing, KONG Li-yuan, ZENG Qi-yao, PANG You-yu, YUAN Shan-liang, LIU Miao
2024,41(11), DOI:
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In this study, WVOx/SiO2 catalysts (CatT, T=350, 400, 450, 500, 600), prepared through impregnation method using industrial mesoporous SiO2 as support, were used in gas-glycerol catalytic conversion. The BET, XRD, NH3-TPD, and XPS results showed that CatT have a well-developed mesoporous structure (d0 5.1-6.8 nm) with specific surface area of 215-235 m2/g. The calcination temperature effectively turned and adjusted the distribution, chemical composition, and acidic strength of WVOx on the surface of SiO2. At 300 ℃, the gas-glycerol conversion over Cat400 reached 89.3%, with the selectivity of acrolein and acetaldehyde reached 53.4% and 22.1%, respectively, and the carbon balance of liquid condensation products reaches 86%. Cat400 also showed good regeneration ability.
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GAO Yu-xuan, GUO Ben-shuai, LUO Yang-na, GUO Ya-fei, ZHAO Chuan-wen
2024,41(11), DOI:
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Copper-based catalysts are highly promising for electrochemical CO2 reduction to value-added products, but they face the challenges of high potential and low products selectivity. Herein, CuS catalysts with different Cu/S ratios were prepared via the hydrothermal synthesis method, and the morphology and structure of the catalysts were characterized by XRD, FESEM, and XPS, to investigate the effect of sulfur content on their “structure-reactivity” relationships in CO2 reduction. Results indicated that sulfur content affected the nucleation and growth of CuS crystals, which in turn exerted impacts on the morphology and sulfur vacancy defects of the catalysts. As the Cu/S ratio varied from 2:1 to 1:4, surface morphology of the catalysts changed from the lotus shape to ball-flower structure, and the concentration of sulfur vacancies increased from 20.66% to 63.37%, which resulted in the significant enhancement of CO2 reduction activity and CO selectivity. The optimum Cu/S ratio was 1:4, and the desired CuS-1:4 catalyst exhibited a high CO selectivity of 72.67% under a mild potential of -0.51 V (reversible hydrogen electrode RHE) in 0.1 M KHCO3 electrolyte. The excellent CO2 reduction performance was associated with the expanded surface area and extended gas diffusion channels provided by the ball-flower structure and the facilitated electron transfer and strengthened adsorption of the *COOH intermediates on the catalyst surface contributed by the abundant sulfur vacancy defects.
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WANG Derong, PANG Fuhua, QIAN Wei, LI Fangyao
2024,41(11), DOI:
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In order to find efficient anti-tumor active molecules,N-(aminosulfonyl)-4-dehydroabietyl carbamates compounds were synthesized from dehydroabietic acid via 3 step reaction and their structures were confirmed by FT-IR, 1HNMR,13CNMR, and ESI-MS. The antitumor activity against T-24, HepG2, MCF-7, MGC-803 and Hela tumor cell lines was evaluated using 5-fluorouracil as positive control. The results showed that the antitumor activity of some compounds was better than that of positive drugs, and compound IVd N-((2-bromophenyl) sulfamyl) -4-dehydroabietyl carbamate showed the best activity against T-24 cell line with IC50 value of 14.64±0.46μmol/L. The primary mechanism was studied by Hoechst 33258 staining, cell colony formation, cell cycle distribution, as well as cell apoptosis and western blotting. The results showed compounds IVd significantly inhibited the growth of T-24 cells and arrested the cell cycle in the S phase. In addition, it could promote T-24 cancer cells apoptosis through upregulation of proapoptotic ones Bax and downregulation of antiapoptotic protein Bcl-2 expression. It is evident that the introduction of sulfanilamide can improve the anti-tumor activity of dehydroabietic acid, which is worthy of further study.
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XIN Mengyao, WU Juan, CHEN Lihong, CHENG Yu
2024,41(11), DOI:
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Potato protein (PP), extracted from fresh potato by the alkali-soluble acid-precipitation method, was mixed with whey protein to fabricate the composite protein emulsion gel. The effect of PP to WP ratios (10:0, 7:3, 5:5、3:7, 0:10, w:w) on characteristics of mixing potato and whey protein emulsion gels were investigated by FTIR, low-field nuclear magnetic resonance (LF-NMR), scanning electron microscopy (SEM), Confocal laser scanning microscopy (CLSM), rheological and textural analysis, chrominance, and intermolecular force. The results showed that the comprehensive properties of composite protein emulsion gel were better than those of single potato protein or whey protein emulsion gel. The storage modulus(G") of the composite emulsion gels with the PP to WP ratio of 7:3 and 5:5 was 114.7% and 108.7% higher than that of the PP emulsion gels (PP: WP=10:0) (p<0.05). The gel strength, elasticity, adhesiveness, resilience, and chewability of composite emulsion gels with the PP to WP ratio of 7:3 and 5:5 were higher than those of PP emulsion gels (p<0.05). CLSM and SEM showed that the emulsion gels with the PP to WP ratio of 7:3 and 5:5 have dense networks and well-distributed emulsified oil droplets. The emulsion gels" primary secondary protein structure was β-helix and β-turn, which account for about 70%.
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dingmiao, chengyuan, lishuang, fanziluan, wangsiyu
2024,41(11), DOI:
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To evaluate the effect of origin on Tartary buckwheat"s active ingredients, antioxidant capacity, and hypoglycemic activity, Tartary buckwheat in seven different production areas as the object of study, firstly, to determine its active ingredients (total polyphenols, total flavonoids, and D-chiral myo-inositol), antioxidant capacity (DPPH free radicals, ABTS + radical scavenging rate) and hypoglycemic activity (inhibition of α-glucosidase and α-amylase), and then by principal component analysis and cluster analysis for multi-factor statistical analysis. The results showed that the active ingredients, antioxidant capacity, and hypoglycemic activity of Tartary buckwheat from different production areas have significant differences. Tartary buckwheat (DT) in North China, had the highest total polyphenol [in gallic acid (GAE)] and D-chiral inositol (DCI) content, respectively, 37.24±0.48 mg (GAE)/g and 3.97±0.32 mg (DCI)/g; total polysaccharide content [in glucose (DE)] was the lowest, 14.42±0.38 mg (DE)/g; on the DPPH radicals and ABTS + radical scavenging ability is the strongest, half scavenging mass concentration of 0.630±0.075 and 0.119±0.008 g/L; α-glucosidase and α-amylase half of the inhibition of the mass concentration of 1.228±0.056 and 1.327±0.146 g/L. A kind of Tartary buckwheat (SQ) in central China, the total flavonoids [as rutin ( RE)] content was the highest, 15.47±0.19 mg (RE)/g. A buckwheat (QJ) in Southwest China had the highest content of total polysaccharides, 24.98±0.75 mg (DE)/g. The antioxidant capacity and hypoglycemic activity of the active ingredients are total polyphenols, total flavonoids, and D-chiral inositol.
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ZHANG Chen, Li Xiao-tian, DING Ming-hui, ZHU Huai-qing, MING Li-jun, LIU Xin-yu
2024,41(11), DOI:
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A long chain flame retardant (PhN-DOPO) was synthesized from p-aminobenzoic acid, p-hydroxybenzaldehyde and 9,10-dihydro-9-oxa-10-phosphame-10-oxide (DOPO). The results were confirmed by FTIR, 1HNMR and ESI-MS characterization. A series of gradient modified epoxy resins (EP1~EP4) with the addition amount of PhN-DOPO (the addition mass was the percentage of the mass of epoxy resin, the same below) of 0%, 5%, 10% and 15% were prepared. The thermal stability, flame retardancy and bond performance of the modified epoxy resin were investigated by DSC, TGA, LOI, UL-94 and bonding properties. The results showed that the glass transition temperature (Tg) of the modified epoxy resin EP3 increased to 177.2 ℃, the UL-94 test was V-0 grade, and the LOI reached 32.4%, which showed the best flame retardancy and good thermal stability when the PhN-DOPO content was 10%. The bond strength of EP3 was 68.82 N, 6.89 N higher than that of pure epoxy resin (EP1). During the combustion of the modified epoxy resin, PhN-DOPO improved the flame retardancy of the epoxy resin through the synergistic effect of condensed phase and gas phase flame retardancy, and the gas phase flame retardancy of the modified epoxy resin was more significant because the degree of graphitization of the residual carbon was reduced.
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LIU Xiaohui, HUANG Jiaying, XUE Can, ZHOU Xiantai
2024,41(11), DOI:
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Selective oxidation of C?H bonds under mild conditions plays an important role in the production of fine chemicals. Inspired by the active center structure and catalytic cycle of galactose oxidase (GOase), the biomimetic model compound CuL was used as a catalyst and N-Hydroxyphthalimide (NHPI) was used as a co-catalyst. Under mild conditions (O2 1.0 MPa, 75 °C, 6 h), the conversion of ethylbenzene was as high as 99%, and the selectivity of the oxidation product acetophenone was as high as 99%. Mechanistic studies showed that CuL forms an intermediate with NHPI, which efficiently promotes NHPI to generate PINO (phthalimide N-oxyl) radicals through electron transfer. PINO radical was used to activate C?H bonds. KIE experiment (KNHPI-H/KNHPI-D ≈ 3.4) indicated that the activation of NHPI was the rate-determining step. Electron paramagnetic resonance (EPR) and high-resolution mass spectrometry pointed out that the existence of alkyl radicals, peroxy radicals and hydroxyl radicals during the reaction.
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CAO Yang, CUI Wen-hui, LI Qian, WU Qing-kun, GAO, Hui
2024,41(11), DOI:
Abstract:
Using 4-cyano-3-methoxybenzaldehyde and tert-butyl acetoacetate as raw materials, finerenone racemes were obtained through condensation, cyclization, oxyalkylation, hydrolysis and ammonolysis, which broke through the difficulty of hydrolysis of conventional esters. A series of optimization of reaction conditions were carried out, and the finerenone racemes were obtained with a total yield of 33.5%. The results showed that the reaction conditions were mild and the yield was high, which provided a reasonable route for the synthesis of finerenone raw materials. The structure of the product was determined by 1 HNMR, 13CNMR and HRMS.
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WANG Jin-long, FAN Ji-xia, LIU Qi-xing, ZHOU Hai-feng
2024,41(11), DOI:
Abstract:
In recent years, mechanical grinding chemistry has attracted much attention by synthetic chemists for its solvent-free conditions. Here we reported a method for the selective oxidation of sulfides to prepare sulfoxides or sulfones by ball milling at room temperature without solvent. A series of sulfones or sulfoxides were selectively prepared with 90%~99% yields from sulfides by adjusting the size and number of grinding balls (proportion of large, medium and small is 20∶40∶100), ball milling time (5~50 min), rotational velocity (400 rpm) and equivalents of Oxone (1~4 mmol) as an oxidant under grinding conditions. All the structures were confirmed by 1HNMR and 13CNMR. This method has benefits of good selectivity, high yield, and wide substrate tolerance, which expands the application scope of mechanochemistry.
