With dodecylamine，methyl acrylate and terephthaloyl chloride as raw material, Sodium N,N′-dilauroylterephthaloylamide propionate acid (SDPA-12) is synthesized by addition, amidation reaction and saponification. The influences of the reaction temperature, the reaction time and the ratios of reactants on the conversion in the amide reaction were investigated. The optimum reaction conditions were: n ( N-dodecyl-β-amino propionate acid methyl ester )：n (terephthaloyl chloride) = 2.2：1, reaction temperature is 35 ℃ and reaction time is 8 h, under these conditions, the conversion of terephthaloyl chloride is 68.7%. The SDPA-12’s structure were proved by Elemental analyzer, IR and NMR, (The SDPA-12’s structure were proved by confirming DPA-12’s structure, DPA-12: N,N′-dilauroylterephthaloylamide propionate acid). Experimental results show that SDPA-12 had a good surface activity, which the surface tension is 27.09 mN/m, and the critical micelle concentration is 1.83?0-5mol/L.