The viscosity, surface/interfacial activity and adsorption of copolymer acrylamide/2-acrylamido-2-methylpropanesulfonic acid/Octylacrylamide (HPPS) and petroleum sulfonate mixed system were studied. And the interaction was discussed. The results show that the viscosity of petroleum sulfonate/1.5g/L polymer HPPS mixed system increases as increasing the mass concentration of petroleum sulfonate, and reaches the maximum at mass concentration 2.0g/L, then viscosity declines fast. The surface tension of the mixed system is lower than that of single petroleum sulfonate when petroleum sulfonate mass concentration is below 0.5g/L, then the surface tension of the mixed system is higher than that of single petroleum sulfonate as the mass concentration increases. The interfacial tension between the mixed system and oil is higher than that of single petroleum sulfonate, but the minimum can reach 10-2mN/m. In polymer HPPS and 2.0g/L petroleum sulfonate mixed system the static adsorption of petroleum sulfonate on the reservoir sand increases as increasing the mass concentration of polymer HPPS, and reaches the maximum at HPPS mass concentration 3.0g/L.