Abstract:The physical and chemical properties of Tetracalcium phosphate (TTCP) +Monocalcium phosphate monohydrate (MCPM) +β-Tricalaium phosphate (β-TCP) bone cements with polyacrylic acid (PAA) hardening liquid have been studied. The results showed that the increasing of the liquid to powder ratio caused an increase in the setting time of cements which allows the possibility for their control, the final setting time was 7min when the liquid to powder ratio was 1.0; Compressive strength was also influenced by the liquid to powder ratio, when the liquid to powder ratio was 0.8, it reached the maximum 20.86 MPa. The degradation rate guadully increased along increasing immersion time, then attained stable. From XRD phase analysis, it was found that Hydroxyapatite (HA) and Dicalcium phosphate dihydrate (DCPD) were created in the setting process, suggesting that the various crystal phase in bone cement resulted in different degradation rate.