The catalyst of ZrOCl2 8H2O supported on molecular sieves USY was prepared using impregnation method and characterized by XRD and SEM. The catalytic properties were examined by the catalytic esterificaton of lauric acid and lauryl alocohol. Used the conversion of lauric acid as an index, the effects of catalyst activity and others conditions such as reaction solvent, catalyst loadings, and reaction time on the conversion of lauric acid were investigated. The results showed that the conversion of lauric acid was up to 95.2 % in the esterification of lauric acid and lauryl alocohol under the optimum conditions of 5.0 % quantity of catalysts, eflux temperature of solvent and reaction time of 16 h by used the 30 % ZrOCl2•8H2O/USY as catalyst and chlorobenzene as solvent.