The Iridium catalytic systems composed of the [IrHCl2(COD)]2 and the chiral diaminodiphosphine ligand was applied for the asymmetric transfer hydrogenation of propionphenone in synthesis of (S)-(-)-1-phenyl-1-propanol. Influence of temperature, substrate/catalyst molar ratio, metal complex/chiral ligand molar ratio was tested. The 94.5% of conversion and 96.0% ee was achieved when propionphenone was reduced 6 hour in this catalytic system.