Achieving macromolecular chain ambient cross-linking to form a network structure in acrylic resin leather coating process is a kind of widely adopted current technical ideas and methods. The mechanisms and ways of that are also hot spots in the current acrylic resin emulsion preparation research field. This paper reviews that the current situation of ambient cross-linking systems in acrylic resin leather finishing and emphatically introduces the research of late-model ambient cross-linking systems in that.