Abstracts:In order to evaluate the safety of starch-based alkyl polyglycosides, the acute dermal toxicity test of mice, acute eyes and skin stimulation tests on rabbits, multiple eyes and skin irritation and skin allergy tests on rabbits were conducted according to the standard GB7919-78. The results showed that the C0810、C1200、C1214 starch-based alkyl polyglycosides surfactant had no acute dermal toxicity and eye stimulation. They didn’t cause irritation or allergy to skin. The allergic reaction rate is 0. Thus they are more secure and reliable in practice.