Abstract: A series of mesoporous strontium-doped titania (Sr-TiO2) materials were synthesized by solid-phase route. These materials were characterized using XRD, TEM, UV-Vis, BET, Raman measurement techniques; their photocatalytic activities were evaluated by measuring the photodegradation of O-nitrophenol solution under UV irradiation. The results showed that the crystal lattice of Sr-TiO2 was anatase phase, the special surface area of a typical product was 160.9m2/g, and pore size distribution was 7.2 nm. Because of Strontium doping, there was slight distortion in the crystal structure of TiO2, and Red-Shift can be seen on absorption band; Under UV irradiation, the photodegradation performance of Sr-TiO2 was improved obviously compared with that of pure TiO2, reached 98.2% in 2 hours. The photocatalytic efficiency reached the maximum when the initial concentration Of O-nitrophenol solution was 30 mg/L and catalyst amount was 1.2g/L.