In this paper, organic, inorganic and organic/inorganic composite antibacterial agents were reviewed through introduction of the type, mechanism, research status and prospects of the agents. Numerous studies showed that achieving high antibacterial efficiency, safety, persistency and stability of antibacterial agents were always projects of design and application of the agents. Derivatization of natural antibacterial agents, polymerization of organic synthetic antibacterial agents and composition of organic and inorganic agents are all research work for the projects and also development direction of antibacterial agents.