Nine macroporous resins with different polarities were evaluated for the static adsorption of quinoxalone. Adsorption kinetics curves and adsorption isotherm of quinoxalone were studied at 25℃ and the process of adsorption was simulated with Langmuir and Freundlich equations. The results showed that XAD16 and HPD-100 resins displayed higher adsorption and desorption performance for quinoxalone than the other resins. Their adsorption capacity and desorption ratio were higher than 600 μg/g dry resin and 70%, respectively. Comparing the correlation coefficient of Langmuir and Freundlich equation, .the former were 0.9726 and 0.9871,respectively; the latter were 0.8879 and 0.9412, respectively。So, D101 was the better and the adsorption capacity arrived to 976 μg per gram dry resin. It was concluded that D101 resin was the ideal macroporous resin for the adsorption of quinoxalone from the fermentation broth of myxobacteria Stigmatella WXNXJ-B.