The research of this thesis is conducted in micro-channel reactor and the synthesis process of preparing epoxidized fatty acid methyl esters from using fatty acid methyl esters as raw materials . Different reaction conditions including mole ratio of catalyst, resident time, amount of H2O2 and HCOOH, reaction temperature, as well as their effects on epoxidation was tested and evaluated. The optimum conditions were determined as follows：m（fatty acid methyl esters）︰m（HCOOH）︰m（H2O2）=1︰1.5︰2，temperature 40℃， the amount of catalyst 3%， reaction time 110s. The epoxy value is 4.32% under this condition.