A new type of amphiphilic chitosan was synthesized by the attachment of succinyl group and lauroyl group to the CS backbone. Modification was confirmed by FTIR and 1H-NMR.The degree of succinyl,substitution was 41.27%, and the degree of lauroyl substitution was 6.32%. Lauroyl-succinyl chitosan (LSCS) can dissolved at pH<3.0 and pH>6.5,and its solubility decreased in isoelectric point and nearby pH range. The LSCS with long alkyl chain can aggregate in water solution through inter-molecular interaction, so their solutions viscosity increased significantly with the increasing of concentration, and as their concentration was up to 2wt%,, it presents gel-like behavior. The gel was sensitive to NaCl. As the concentration of NaCl increased, the strength of gel decreased.