A asymmetric transfer hydrogenation to synthesize R-3,5-(trifluoro-dimethyl) benzene ethanol from 3,5-Bis(trifluoromethyl)acetophenone in isopropyl alcohol by using [RuCl2(C10H14)2]2 as catalyst and (1S, 2R) - (-) - 1 - amino - 2 - indene alcohol as ligands was discussed in this paper,reaction time 6h, reaction temperature 50℃, catalyst/ligands ratio 1:2.5, Substrate concentration 0.0957mol/L, The conversion rate of the product was 99%. Selective(ee) was 91.2% The target product was characterized by means of FTIR and 1H NMR．