Zn-Mg-Al hydrotalcite nanoflake and Zn-Mg-Al hydrotalcite microstructure constructed by nanoflake had been synthesized via a hydrothermal condition at 120℃ for 10h with Zn(NO3)2、Al(NO3)3 and Mg(NO3)2 as reactants, using CO(NH2)2 as precipitation agent. The size, structure and morphology of as-prepared products were characterized by the XRD, FT-IR,TG-DTA,ICP and SEM, demonstrating that the as-prepared hydrotalcite has morphology of a homogeneous and regular flower-like structures with diameter of about 8μm and the measured thickness of the nanoflake is about 100nm and displayed excellent memory function. A possible formation mechanism of flower-like hydrotalcite was also discussed.