Thermo-responsive hydrogels were synthesized by N-ispropylacrylamide(NIPAM) and acrylamide(AM) with N,N'-methylenebiscrylamide(BIS) as crosslinker, ammonium potassium and sodium bisulfite as initiators. The effects of the properties were studied by the change of feed composition. The results show that with the increase of hydrophilic monomer AM, the swelling ratio, water retention and hardness of P(NIPAM-co-AM) are enhanced. The hardness increases from 84.929g in absence of AM to 1255.222g when AM is 100%. According to DSC, when the dosage of AM increases from 2% to 10%, the LCST of P(NIPAM-co-AM) gel increases from 38.61℃ to 57.95℃. With the decrease of AM content, LCST of P(NIPAM-co-AM) gel declines, the responsibility is improved.