Three four-armed star-shaped poly(ɛ-caprolactone)-b-poly(gluconamidoethyl methacrylate)(4sPCL-b-PGAMA) copolymers with porphyrin core were synthesized via ring-opening polymerization and atom transfer radical polymerization.The structure of the result products was characterized by 1HNMR,GPC and UV-vis.DSC result shows that degree of crystallinity decreased from 73.9 to 0.9,with increasing the weight fraction of hydrophilic poly(gluconamidoethyl methacrylate)(PGAMA) within the copolymers from 0% to 79%,indicating that PGAMA can improve efficiently the crystallization of poly(-caprolactone)(PCL).The fluorescence quenching extent(△I) of tetrakis(4-hydroxylphenyl)-porphyrin(THPPH2),4sPCL24 and 4sPCL24-PGAMA37 with the equal number of potential porphyrin core was investigated by fluorescence probe method,exhibiting △ITHPPH2>△I4sPCL24>△I4sPCL24-PGAMA37,demonstrating that the polymeric skeleton can delay successfully the self-quenching of the porphyrin core.Morphology of 4sPCL-b-PGAMA self-assembled aggregates varied from spherical micelles at 70nm,to worm-like aggregates,finally to vesicles at 200nm, with decreasing the weight fraction of PGAMA from 79% to 21%.Moreover,the UV-vis absorbance increased greatly with adding concanavalin A(Con A) to the copolymer micelles solution,indicating the formation of the bigger cross-linked aggregates in aqueous.This demonstrates that 4sPCL-b-PGAMA has specific recognition with Con A