The surface properties, alkaline and stability of dodecyltrimethylammoniu- m hydroxide (DTAH), sodium dodecyl benzene sulfonate (SDBS) and their mixed system were studied. Result showed that when the molar ratio of DTAH and SDBS was 9:1, the mixed system was improved significantly in reducing the surface tension of the capacity and efficiency, and has good stability and strong alkaline. The critical micelle concentration (cmc), surface tension at cmc (γcmc) and pH value of blend system are 3.02×10-5mol•L-1, 28.10mN•m-1 and 12.46 respectively. Interaction parameter in surface (βσ) and micelles (βm) of DTAH/SDBS mixed system achieved -18.36, -22.69, which reflected good synergism.