By post-crosslinking reaction with piperazine , New poly(styreneiviny benzene) hypercrosslinked adsorption resins of NDA-201 were successfully prepared by chemical modification of macroporous resin of XDA-200. The static adsorption and desorption characteristics for norfloxacinin aqueous solution onto above adsorption resins were studied. A batch sorption experiments showed that NDA-201 resin had high adsorption capacities for norfloxacinin．Equilibrium adsorption data fitted to both Langmuir and Freundlich isotherms in the studied concentration range．Adsorption was exothermic arid basically of physical character．Kinetic analysis showed that the adsorption reaction could be approximated by a Lagergren pseudo-second-order-rate equation for which intraparticle diffusion was the essential rate-controlling step．