Synthesis, characterization and biological activities of Ru(II)–dmso complexes with heterocyclic hydrazones ligands
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    Abstract:

    Two [Ru(Ⅱ)Cl2(DMSO)2L1,2] type complexes were synthesized by mixing precursor complex cis-[RuCl2(DMSO)4] and heterocyclic aldehyde benzoyl hydrazone in ethanol (L1 is pyridine-4-formaldehyde benzoylhydrazone, L2 is furan-2-carboxaldehyde benzoylydrazone) .The new complexes were characterized by elemental analysis, IR spectra , UV-Vis spectra and 1HNMR. The electrochemical behavior of the complexes was studied with the help of cyclic voltammetry, Results indicate that [Ru(Ⅱ)Cl2(DMSO)2L2)] of five strains were used in the experiment has strong antibacterial activity.The antibacterial activity of complexes was detected by agar diffusion method and the anticancer activity of complexes was detected by MTT method, Results showed [Ru(Ⅱ)Cl2(DMSO)2L1] expression of growth promoting effect on cells, [Ru(Ⅱ)Cl2(DMSO)2L2)]Show the promotion before inhibition effect.

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History
  • Received:July 17,2013
  • Revised:October 08,2013
  • Adopted:October 28,2013
  • Online: February 13,2014
  • Published:
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