NiCrCo nano oxides have been synthesized by thermal decomposition method and were used as the anode electrocatalysts for direct methanol fuel cell (DMFC). The catalysts were characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The results show that the particle size of nano oxides was about 20-50 nm, and the material dispersed uniformly. The activity of catalysts with different metal molar ratios and calcination temperatures on the methanol oxidation reaction were investigated by cyclic voltammetry (CV). The optimal content of the Ni:Cr:Co ratio is found to be 1:1:1.5, which exhibits significantly high current density of methanol oxidation. And the onset potential ,current density and If/Ib for methanol oxidation was 0.38 V, 19.3 mA/cm2 and 1.72, respectively. Results show that the prepared NiCrCo nano oxides electrode presents high electrocatalytic activity for methanol oxidation.NiCrCo nano oxides have been synthesized by thermal decomposition method and were used as the anode electrocatalysts for direct methanol fuel cell (DMFC). The catalysts were characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The results show that the particle size of nano oxides was about 20-50 nm, and the material dispersed uniformly. The activity of catalysts with different metal molar ratios and calcination temperatures on the methanol oxidation reaction were investigated by cyclic voltammetry (CV). The optimal content of the Ni:Cr:Co ratio is found to be 1:1:1.5, which exhibits significantly high current density of methanol oxidation. And the onset potential ,current density and If/Ib for methanol oxidation was 0.38 V, 19.3 mA/cm2 and 1.72, respectively. Results show that the prepared NiCrCo nano oxides electrode presents high electrocatalytic activity for methanol oxidation.