2-Hydroxy-4-acryloy benzophenone(HAB) was synthesized from acrylicchloride and 2,4-dihydroxybenzophenone(UV-0). Poly(HAB-OAIG)(PHIG) was prepared by polymerization of HAB with 3-O-acryloyl-1,2,5,6-di-O-isopropynylene-α-D-glucose(OAIG). Then, the copolymer poly(HAB-co-3-O-acryloyl-α-D-glucose)(PHG) was obtained by hydrolysis of PHIG via trifluoroacetic acid. These structures were characterized mainly by FTIR, 1HNMR and GPC. The UV-Vis spectroscopies revealed that PHG is of good ultraviolet absorption ability in the wavelength range of 280-360 nm, and the maximum absorption wavelength is 331 nm. MTT experiments showed the relative cell proliferation rate of L929 cells which were treated with different concentrations extracts of PHG is greater than 80%. And with the concentration increases, the relative appreciation rate was not significantly reduced. These data demonstrated that PHG has good biocompatibility.