The structure, particle size distribution and adsorption performance of 13X zeolites obtained by hydrothermal synthesis system with isopropanol were characterized by XRD, SEM, BET, and ICP-AES etc. It is concluded that with the increasing amount of isopropanol in the synthesis system, 13X zeolites’ relative crystalline, grain size and the silica/alumina ratio are decreased; the pore volume and average pore size are increased. The samples were investigated in removing oxygenates (methanol, DME, etc.) from ethylene under the condition of 1500h-1 (GHSV) and with 1000ppm DME in the feed flow. The results showed that the samples with smaller grain size and larger pore volume had better adsorption performance, Compared with other samples, the sample synthesized from the synthesis system containing 15wt% isopropanol exhibited the best performance, the on stream lifetime reached 280min, and the coking rate was 0.71%/h.