Manganese oxide octahedral molecular sieves (OMS-2) were prepared in high gravity reactor by redox precipitation method. The effects of the amount of acid, the rotation speed of reactor and reaction temperature on the properties of OMS-2 were investigated. SEM images and XRD patterns showed that the crystal structure of OMS-2 formed well when the amount of HNO3 added was 340ml and the rotation speed of reactor was 1200 r?min-1. Size control of OMS-2 was not achieved through changing the rotation speed of reactor, and reaction temperature could significantly alter the size of crystalline materials. Lateral growth rate along the diameter of OMS-2 nanorods rose when reaction temperature increased from 30℃ to 60℃. DSC thermogram and H2-TPR profile indicated that, in comparison with conventional reflux method, persistent release ability of oxygen species of OMS-2 materials synthesized by HGRP was better at temperature below 550℃ and the destruction of crystal structure was needless at the same time. Finally, this study provides a new green method to prepare one-dimensional OMS-2 nanorods on a large scale.