The modified polyacrylonitrile fiber was used as carrier to prepare Pd(II)-AOFs. The catalytic performance of Bromopyridine and Phenylboronic acid coupling reaction on Pd(II)-AOFs was investigated. The results showed that the yield of [Pd(II)-AOFs] could reach 90% under following conditions: Bromopyridine (5 mmol), phenylboronic acid (5.5 mmol), solvent (C2H5OH/H2O, V/V=2:1, 30 ml), base (NaHCO3, 10 mmol), TBAB(10 mol%), reflux reaction time (30 min), Pd (II)-AOFs (0.6 mol%).The reaction also had a good adaptability on Bromopyridine and Phenylboronic acid/Its Derivatives coupling reaction, after repeated seven times the production was still 90%.When added TBAB the reaction time is greatly shorten.