In the preparation of pinacol(4-tert-butylbenzene)boronate by Pd-catalyzed borylation of 4-tert-buty-1-chlorobenzene,Pd2dba3 was used as catalyst,Xphos as ligand and B2(pin)2 as boron source.The effects of the quantity of boron source,different kinds of bases, ratio of the catalyst to the ligand, solvents and temperatures on the yield of the product were studied. The optimum conditions were determined as follows: n(4-tert-butyl-1-chlorobenzene) : n(Pd2dba3) : n(Xphos) ： n[B2(pin)2] : n(KOAc) = 1 : 0.01 : 0.04 : 2 : 3 in EtOH at 60℃ for 1 h.The yield can reach 98%.