A novel compound of 5,15-bis-pentafluorophenyl-10,20-di-(2-pyridyl-) porphyrin was synthesized by two steps. The effects of the dosage of catalytic agent, temperature and time on the yield of target compound were investigated. The results show that the yield of the target compound reaches 33.6% when the molar ratio of catalyst to pentafluoro-benzaldehyde is 1:15, the temperature is 145 ℃ and the reaction time is 1 h. The target product was characterized by MS, IR, UV-Vis, 1HNMR, 19FNMR and EA. Meanwhile, It displays intense fluorescence emission with maximum at 711 nm upon 470 nm excitation at room temperature, indicating that they may be candidate for luminescent material.