The OPGS/PA-APP/PP composite with excellent flame retardancy and good mechanical properties has been prepared. The Organo palygorskite (OPGS) was introduced into the PA-APP/PP flame retardant composite. The OPGS loading on the performance of flame retardancy and mechanical properties of the composite were investigated by the limited oxygen index (LOI), vertical burning test (UL-94), thermogravimetric analysis (TGA), scanning electronic microscopy (SEM) and electronic universal testing machine. The experimental results showed that the addition of 2% of OPGS simultaneously increased flame retardancy of PA-APP/PP composite as well as the tensile strength and bending strength. In addition, the prepared samples could pass the V-0 rating in the UL-94 tests. The OPGS has obvious flame retardant synergistic effect in the IFR/PP system.