Crystallization process of carbamazepine (CBZ) polymorphs was investigated using the biomicroscope, X-ray powder diffraction (XRD), Malvin particle analysis, DSC and FBRM and PVM. The effect of different operation factors such as solvents, seeds, crystallization method, drying, temperature, agitation rate and cooling rate on the properties, especially the polymorph of carbamazepine were investigated. The results show that CBZ dihydrate could be recrystallization from ethanol-water mixture, CBZ form III could be obtained through slow cooling in alcohol solvents, CBZ form II was got by recrystallization in THF. The conformity of the particle could be obtained by adding large amount of fine seeds. The CBZ form II was easy to include solvent because its special structure (the channel). The temperature play a mainly role for the polymorph of CBZ, it gave CBZ form III a lower temperature range (52～20℃), while gave CBZ form II a higher temperature range（90～76℃）. The mean particle size was easy to obtain when the stirring rate was higher.The cooling rate didn’t affect the polymorph of CBZ, all the products were CBZ form III, but there was a difference in crystal size distribution (CSD).